YAKHAK HOEJI

Table. 2.

Table 2 Formulas and criteria for signal detection in data mining indices

2×2 contingency table for measures of disproportionality
	Specific AEs	All other AEs
TDF	A	B
All other NAs	C	D
Indices	Definition	Criteria of signal detection
ROR	A/CB/D	Lower limit of 95% confidence interval>1

Abbreviation: AE, Adverse Event; NA, Nucleotide Analogue; ROR, Reporting odds ratio; TDF, Tenofovir Disoproxil Fumarate.