약학회지

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Table. 7. In vitro dissolution parameters
Run # t25% (hr) t50% (hr) t75% (hr) MDT (hr)
1 0.67 4.32 14.25 7.90
2 1.07 5.09 10.66 7.38
3 0.743.97 10.67 6.33
4 0.35 2.69 08.01 9.47
5 1.73 4.72 12.15 7.97
6 2.21 6.56 12.61 10.510
7 0.46 2.50 06.91 4.31
8 0.71 2.90 08.06 4.45
9 0.78 3.66 09.10 4.99
Reference 0.98 3.56 23.97 5.12
Optimized 0.97 3.27 23.22 9.63

MDT (Mean dissolution time) = (n/n+1)×K-1/n

Yakhak Hoeji 2024;68:252-68 https://doi.org/10.17480/psk.2024.68.4.252
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