ISSN 0377-9556 (PRINT)
ISSN 2383-9457 (ONLINE)
ISSN 2383-9457 (ONLINE)
Cases of GLP-1 RA | Non-cases of GLP-1 RA | ROR (95% CI) | Signal† | |
---|---|---|---|---|
Biliary tract disorders |
||||
America | 26 | 11,614 | 2.79 (1.79-4.35) | O |
Europe | 57 | 21,012 | 0.63 (0.48-0.83) | X |
Asia | 13 | 2,899 | 1.65 (0.94-2.90) | X |
Other regions | 0 | 358 N/A | N/A | |
Gallbladder-related disorders |
||||
America | 147 | 11,493 | 11.31 (8.82-14.49) | O |
Europe | 119 | 20,950 | 7.06 (5.35-9.31) | O |
Asia | 37 | 2,875 | 5.32 (3.71-7.62) | O |
Other regions | 1 | 357 | 1.69 (0.22-13.01) | X |
Abbreviations: ROR, Reporting Odds Ratio; CI, Confidence Interval; WHO-UMC, World Health Organization-Uppsala Monitoring Centre
*The Adverse Events of interest are defined using Standardized MedDRA Queries (SMQ)
†Safety signals detection with ROR were assessed as AEs where thresholds of ROR were greater than one.