약학회지

ISSN 0377-9556 (PRINT)
ISSN 2383-9457 (ONLINE)

Table. 1.

Table. 1. IC50 values of the TKIs and W1 compounds against A549, H1975, PC9 and PC9GR cells for 48 h
Compounds IC50 (μM)a
A549 H1975 PC9 PC9GR
Sorafenib >27 >30 21±1.6 27.2±1.69
Imatinib >30 >30 >30 >30
Poziotinib >30 12±2.5 8.0±2.3 25.6±1.4
Dasatinib >30 >30 18.7±2.1 26.8±5.20
Nilotinib >30 >30 >30 >30
W1 >30 >30 8.6±4.8 22.3±1.5

aThe inhibitory activities of compounds were measured using the MTT assay. The data is shown by Mean±SD of 3 independent experiments.

Yakhak Hoeji 2024;68:94-7 https://doi.org/10.17480/psk.2024.68.2.94
© 2024 Yakhak Hoeji