약학회지

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Table. 2.

Table. 2. IC50 values of the TKIs and W1 - W12 compounds against PC9 and PC9GR cells for 48 h
Compounds IC50 (μM)a
PC9 PC9GR
Poziotinib 8.0±2.3 25.6±1.4
W1 8.6±4.8 22.3±1.5
W2 10.7±5.5 27.4±1.7
W3 3.3±0.2 17.9±3.4
W4 26.3±0.1 >30
W5 10.4±2.2 >30
W6 21.2±1.1 >30
W7 12.3±2.8 24.4±4.8
W8 20.7±1.5 >30
W9 >30 >30
W10 >30 >30
W11 >30 >30
W12 >30 >30

aThe inhibitory activities of compounds were measured using the MTT assay. The data is shown by Mean±SD of 3 independent experiments.

Yakhak Hoeji 2024;68:94-7 https://doi.org/10.17480/psk.2024.68.2.94
© 2024 Yakhak Hoeji