약학회지

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Table. 5.

Table. 5. Pharmacokinetic parameters of paeoniflorin in Rat (n=4 for each data point)
Ext+L Oral administration I.V injection
AUC (ng · hr/ml) 3122.66±199.64 4191.20±251.07
Tmax(min) 180 -
Cmax(ng/ml) 1269.65±138.92 5173.80±51.74
F (%) 7.45 100

*Significant differences are indicated with ‘*’ at p<0.05 compared with Oral administration group.

AUC : Area Under the Curve)

Cmax(ng/ml) : Cmax refers to the peak or maximum concentration of a drug in the bloodstream

Tmax(min): Tmax indicates the time taken to reach that peak concentration after administration.

F (%) : F in pharmacokinetic parameters represents bioavailability, indicating how much a drug is absorbed and becomes effective in the body.

Yakhak Hoeji 2023;67:372-7 https://doi.org/10.17480/psk.2023.67.6.372
© 2023 Yakhak Hoeji