YAKHAK HOEJI

Table. 5.

Table 5Accelerated stability of Sarpodipil^Ⓡ SR and developed OROS tablet at 40℃ / 75% RH (Mean±SD, n=3)

Month	Item	Sarpodipil^Ⓡ SR	Developed OROS tablet
Initial	Content (%)	96.96±0.08	96.37±0.35
	*Total BP-984 (%)	0.003±0.001	0.003±0.001
	Dissolution rate at 24 hr (%)	94.30±0.10	93.00±0.24
2	Content (%)	98.00±0.15	96.40±0.11
	Impurity (%)Total ImpurityBP-984 (%)	0.007±0.001	0.010±0.001
	Dissolution rate at 24 hr (%)	94.40±0.60	92.90±0.63
3	Content (%)	96.70±0.73	96.33±0.47
	Impurity (%)Total ImpurityBP-984 (%)	0.010±0.001	0.020±0.002
	Dissolution rate at 24 hr (%)	94.70±0.50	92.20±0.90