Fig. 3. Atorvastatin increases ROS generation. (A) B16F10.OVA cells were treated with various concentration of Atorvastatin, Ferrostatin-1, RSL3 for 24h. Cells were stained with H₂DCF-DA to quantify the ROS generation. The percentage of ROS derived from the histogram of the flow cytometry analysis are shown in representative images. (B) Quantification of the percentage of ROS derived from the histograms in panel (A). The data are shown as mean±SEM (n=3). Statistical significance was marked as *p<0.05, **p<0.01, ***p<0.001 and ****p<0.0001

Yakhak Hoeji 2023;67:261-7 https://doi.org/10.17480/psk.2023.67.4.261

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