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ISSN 2383-9457 (ONLINE)
Fig. 2. Atorvastatin increases Fe2+ accumulation. (A) B16F10.OVA cells were treated with various concentration of atorvastatin, ferrostatin-1 and RSL3 for 24h. Cells were stained with ferroOrange to quantify the amount of Fe2+. The percentage of Fe2+ accumulation derived from the histogram of the flow cytometry analysis are shown in representative images. (B) Quantification of the percentage of Fe2+ accumulation derived from the histograms in panel (A). The data are shown as mean±SEM (n=3). Statistical significance was marked as *p<0.05, **p<0.01, ***p<0.001 and ****p<0.0001
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