약학회지

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Table. 3.

Table. 3.

Aqueous solubility of enzalutamide in various 1% (w/v) polymer solutions. Each value represents the mean±SD (n=3)

Polymer Enzalutamide conc. (μg/mL)
Mean±SD
D.W (control) 1.88±0.12
HP-β-Cyclodextrin 6.72±0.17
β-Cyclodextrin 6.48±0.39
γ-Cyclodextrin 6.10±0.14
Carbopol 934NF 3.68±0.59
Xanthan gum 3.11±0.84
Carbopol 941NF 3.03±0.57
HPC-L 2.64±0.02
HPMC 2208 4000cp 2.62±0.55
HPMC 2910 P-645 2.53±0.22
Kollidon VA64 2.41±0.31
Kollidon SR 2.24±0.19
Gelatin 2.04±0.43
PVP K30 1.78±0.38
Sodium alginate 1.66±0.41
Arabic gum 1.43±0.22
α-Cyclodextrin 1.32±0.09
Maltodextrin 1.16±0.07
Yakhak Hoeji 2022;66:283-91 https://doi.org/10.17480/psk.2022.66.5.283
© 2022 Yakhak Hoeji