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Fig. 2.

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Fig. 2. Nimbolide inhibits OVA-induced immune cell accumulation in broncho-alveolar lavage fluid (BALF). (A) Mice were sensitized with OVA twice by i.p. injection on D0 and D14, and were later challenged on D28, D29, and D30 with nebulized OVA. Nimbolide was treated intraperitoneally at a dose of 1 mg/kg, 30 min before the OVA challenge. Cells in BALF were stained using May-Grünwald stain and counted. (B) Total cell counts, eosinophils, and macrophages in BALF. (C) Lymphocyte counts in BALF. The results are presented the mean±SE cell count values (n=5). ***p<0.001 vs. the PBS-treated group, ##p<0.01, ###p<0.001 vs. the OVA-treated group.
Yakhak Hoeji 2022;66:217-24 https://doi.org/10.17480/psk.2022.66.5.217
© 2022 Yakhak Hoeji