ISSN 0377-9556 (PRINT)
ISSN 2383-9457 (ONLINE)
ISSN 2383-9457 (ONLINE)
Factors associated with BRONJ using multivariable logistic regression analysis
| Variable | Crude odds ratio (95% CI) | Adjusted odds ratio (95% CI) |
|---|---|---|
| Comorbidities | ||
| Breast Cancer | 1.05 (0.63–1.78) | 0.78 (0.45-1.35) |
| Prostate Cancer | 1.32 (0.96-1.92) | 0.82 (0.55-1.23) |
| Hypertension | 1.25 (1.16-1.34) | 1.04 (0.96-1.13) |
| Hyperlipemia | 1.24 (1.16-1.33) | 0.96 (0.89-1.04) |
| Arthrosis | 1.77 (1.65-1.90) | 1.58 (1.47-1.71) |
| Rheumatoid arthritis | 1.83 (1.65-2.02) | 1.46 (1.30-1.63) |
| Neuropathies | 1.58 (1.46-1.71) | 1.31 (1.20-1.42) |
| Anemia | 1.65 (1.51-1.81) | 1.32 (1.20-1.45) |
| Co-medication | ||
| Antiplatelet | 1.27 (1.1951.36) | 1.09 (1.01-1.18) |
| Route of administration | ||
| Bisphosphonates oral | 1.32 (1.10-1.58) | 1.55 (1.28-1.88) |
| Bisphosphonates injections | 1.47 (1.28-1.67) | 1.52 (1.32-1.76) |
| Tooth extraction | 1.65 (1.54-1.77) | 1.64 (1.53-1.76) |
| Charlson comorbidites | ||
| Myocardial infarction | 1.60 (1.33-1.93) | 1.23 (1.01-1.49) |
| Congestive heart failure | 1.31 (1.18-1.45) | 1.04 (0.93-1.16) |
| Peripheral vascular disease | 1.35 (1.25-1.46) | 1.09 (1.00-1.18 |
| Cerebrovascular disease | 1.12 (1.04-1.21) | 0.88 (0.80-0.97) |
| Renal disease | 1.91 (1.57-2.34) | 1.36 (1.10-1.68) |
| Cancer | 1.49 (1.33-1.67) | 1.27 (1.12-1.45) |
| Rheumatic disease | 2.07 (1.70-2.53) | 1.24 (0.99-1.55) |
| Peptic ulcer disease | 1.40 (1.31-1.50) | 1.09 (1.01-1.17) |
| Mild liver disease | 1.26 (1.17-1.36) | 0.95 (0.87-1.04) |
| Diabetes without chronic complication | 1.46 (1.36-1.57) | 1.18 (1.08-1.28) |
| Diabetes with chronic complication | 1.45 (1.32-1.59) | 1.06 (0.95-1.18) |
| Hemiplegia or paraplegia | 1.2 (0.99-1.46) | 1.04 (0.85-1.28) |
| Liver disease | 2.14 (1.46-3.17) | 1.63 (1.10-2.43) |
| Metastatic solid tumor | 1.57 (1.16-2.21) | 1.09 (0.78-1.52) |
| AIDS | 1.33 (0.13-12.81) | 1.15 (0.11-11.76) |