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Fig. 5.

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Fig. 5. Effect of hyperoside on the phosphorylation of MEK1/2, p38, and p44/42 in NCI-H292 cells. NCI-H292 cells were pretreated with hyperoside (20 μM) for 24 h and then stimulated with epidermal growth factor (EGF) (25 ng/mL) for the indicated periods. Whole cell extract was collected and western blot analysis of the cellular proteins with anti-phospho-MEK1/2 (Ser221), anti-phospho-p38 MAPK (Thr180/Tyr182), anti-phospho-p44/42 (Thr202/Tyr204) antibodies was conducted. Three independent experiments were performed and the representative data were shown. cont: control, H: hyperoside, MAPK: mitogen-activated protein kinase, ERK: extracellular signalregulated kinase, MEK: MAP kinase kinase, H20: hyperoside 20 μM, concentration unit is μM.
Yakhak Hoeji 2022;66:104-9 https://doi.org/10.17480/psk.2022.66.2.104
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