약학회지
YAKHAK HOEJI
ISSN 0377-9556 (PRINT)
ISSN 2383-9457 (ONLINE)

Fig. 2.

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Fig. 2. Effect of rosiglitazone, metformin, thioctic acid, simvastatin, or glimepiride on PMA-induced MUC5AC gene expression in NCI-H292 cells. NCI-H292 cells were pretreated with varying concentrations of rosiglitazone, metformin, thioctic acid, simvastatin, or glimepiride for 30 min and then stimulated with PMA (10 ng/mL) for 24 h. MUC5AC gene expression was measured by RT-PCR. As a quantitative control, primers for Rig/S15 rRNA, which encodes a small ribosomal subunit protein, a housekeeping gene that was constitutively expressed, were used. Three independent experiments were performed and the representative data were shown (A-E). (cont: control, R: rosiglitazone (A), M: metformin (B), T: thioctic acid (C), S: simvastatin (D), G: glimepiride (E), concentration unit is μM.)
Yakhak Hoeji 2021;65:424-31 https://doi.org/10.17480/psk.2021.65.6.424
© 2021 Yakhak Hoeji