약학회지
YAKHAK HOEJI
ISSN 0377-9556 (PRINT)
ISSN 2383-9457 (ONLINE)

Table. 2.

Table. 2.

Pharmacokinetic parameters of Ptx in rat plasma after oral administration of Ptx solution and Ptx-LNCs (12 mg/kg as Ptx) to rats

Parameters Oral administration

Paclitaxel solution Ptx-LNCs
AUCt (µg·h/mL) 26.93±4.80 49.84±2.07*
Tmax (h) 4.15±0.52 3.54±1.09
CL/F (mL/h) 445.55±79.60 240.97±100.66*
Cmax (µg/mL) 1.57±0.01 2.70±0.39*

*p<0.05 (n=3).

Yakhak Hoeji 2021;65:375-85 https://doi.org/10.17480/psk.2021.65.5.375
© 2021 Yakhak Hoeji