약학회지
YAKHAK HOEJI
ISSN 0377-9556 (PRINT)
ISSN 2383-9457 (ONLINE)

Fig. 5.

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Fig. 5. Involvement of NOX in the dRP-induced KCC activation in B16 melanoma cells. The data (A) and (C) represent intracellular K+ and Cl changes with time, respectively. The arrows show the time point for addition of dRP (100 μM). In these experiments DPI (50 μM) and Apo (100 μM) were used as NOX inhibitors. In the data (B) and (D), quantitative changes of K+ and Cl efflux were expressed as a percentage of control condition compared to control condition in which the cells were treated with a drug-free vehicle. *p<0.05 compared to negative control. #p<0.05 compared to dRP alone. Abbreviations: Apo, apopcynin; DPI, diphenyleneiodonium; dRP, deoxyribose 1-phosphate; KCC, K+-Cl-cotransport; NOX, NADPH oxidase.
Yakhak Hoeji 2021;65:363-9 https://doi.org/10.17480/psk.2021.65.5.363
© 2021 Yakhak Hoeji