약학회지
YAKHAK HOEJI
ISSN 0377-9556 (PRINT)
ISSN 2383-9457 (ONLINE)

Fig. 3.

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Fig. 3. Activation of KCC induced by dRP in B16 melanoma cells. The data (A) and (C) represent intracellular K+ and Cl changes with time, respectively. The arrows show the time point for addition of dRP (100 μM). In these experiments DIOA (100 μM) was used as a KCC inhibitor. In the data (B) and (D), quantitative changes of K+ and Cl efflux were expressed as a percentage of control condition compared to control condition in which the cells were treated with a drug-free vehicle. *p<0.05 compared to negative control. #p<0.05 compared to dRP alone. Abbreviations: DIOA, R-(+)-[(2-n-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]acetic acid; dRP, deoxyribose 1-phosphate; KCC, K+-Cl-cotransport.
Yakhak Hoeji 2021;65:363-9 https://doi.org/10.17480/psk.2021.65.5.363
© 2021 Yakhak Hoeji