약학회지
YAKHAK HOEJI
ISSN 0377-9556 (PRINT)
ISSN 2383-9457 (ONLINE)

Fig. 2.

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Fig. 2. Role of ROS produced by NOX in the dRP-induced melanogenesis in B16 melanoma cells. The data (B) show changes in ROS levels as a function of time. The arrow shows the time point for addition of dRP (100 μM). In these experiments DPI (50 μM) and Apo (100 μM) were used as NOX inhibitors. In the data (A) and (C), quantitative changes in melanin contents and ROS, respectively, are expressed as a percentage of control condition in which cells were grown in medium without dRP. *p<0.05 compared to negative control. #p<0.05 compared to dRP alone. Abbreviations: Apo, apopcynin; DPI, diphenyleneiodonium; dRP, deoxyribose 1-phosphate; NOX, NADPH oxidase; ROS, reactive oxygen species.
Yakhak Hoeji 2021;65:363-9 https://doi.org/10.17480/psk.2021.65.5.363
© 2021 Yakhak Hoeji