약학회지
YAKHAK HOEJI
ISSN 0377-9556 (PRINT)
ISSN 2383-9457 (ONLINE)

Fig. 5.

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Fig. 5. 20(R)-Rg3 improves wound closure in the early stages of wound healing, whereas 20(S)-Rg3 has no effect. (A) Representative photographs of wounds on the skin of BALB/c mice treated with 20(R)-Rg3 and 20(S)-Rg3 diluted in PBS at a 100 μM concentrations, showing the macroscopic wound closures on days 0, 7, and 15 after injury, compared with control mice treated with DMSO. (B) Ratios of wound areas on day 7 and day 15 vs. the initial area on day 0 after treatment with DMSO (control), 20(R)-Rg3, or 20(S)-Rg3 treatment. Seven days after surgery, mice treated with 20(R)-Rg3 had lower wound area ratios than mice treated with DMSO. By contrast, mice treated with 20(S)-Rg3 exhibited no difference in wound area ratio relative to the control group. NSp>0.05, *p≤0.05 vs. DMSO (control).
Yakhak Hoeji 2021;65:65-71 https://doi.org/10.17480/psk.2021.65.2.65
© 2021 Yakhak Hoeji