ISSN 0377-9556 (PRINT)
ISSN 2383-9457 (ONLINE)
ISSN 2383-9457 (ONLINE)
Specific strong index inhibitors, inducers, and sensitive index substrates of cytochrome P450 (CYP)
| CYP450 | Strong index inhibitors | Strong index inducers | Sensitive index substrates |
|---|---|---|---|
| CYP1A2 | fluvoxamine | montelukast (moderate) | caffeine, tizanidine |
| CYP2B6 | ticlopidine (weak) | rifampin (moderate) | bupropion, efavirenz |
| CYP2C8 | clopidogrel, gemfibrozil | rifampin (moderate) | repaglinide |
| CYP2C9 | fluconazole (moderate) | rifampin (moderate) | warfarin, tolbutamide |
| CYP2C19 | fluvoxamine | rifampin | S-phenytoin, omeprazole |
| CYP2D6 | fluoxetine, paroxetine | atomoxetine,desipramine, dextromethorphan | |
| CYP3A4 | clarithromycin, itraconazole | phenytoin, rifampin | midazolam, triazolam |